Zydus Cadila's ZyCoV-D has got its first coronavirus vaccine for the adolescents in the 12-18 age group. This is world's first plasmid DNA vaccine for COVID-19. This will be a three-dose vaccine. The vaccine will be administered needle-free using 'PharmaJet', a needle-free applicator, which ensures painless intradermal vaccine delivery. The company plans to manufacture 10-12 crore doses of ZyCoV-D annually. Zydus Cadila says this is for the first time that a technologically advanced vaccine has been successfully developed on the Plasmid DNA platform for human use. They are a valuable form of antigen-specific immunotherapy, as they are safe, stable and can be easily produced.